⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231424 | 0.90 | — | — | |
| SCHEMBL8208077 | 0.87 | — | — | |
| SCHEMBL2449857 | 0.87 | — | — | |
| SCHEMBL3628409 | 0.87 | — | — | |
| SCHEMBL3626508 | 0.87 | — | — | |
| SCHEMBL3626234 | 0.87 | — | — | |
| SCHEMBL8212987 | 0.87 | — | — | |
| SCHEMBL3628842 | 0.87 | — | — | |
| SCHEMBL979431 | 0.87 | — | — | |
| SCHEMBL1278716 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2642 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321573-B | Substituted pyrimidine compound as phosphatidylinositol 3-kinase delta inhibitor and application thereof | 南京圣和药业股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-112321573-A | Substituted pyrimidine compound as phosphatidylinositol 3-kinase delta inhibitor and application thereof | 南京圣和药业股份有限公司 | 2021-02-05 | — | — | CN | claimed |
| EP-3266774-B1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2019-09-04 | — | — | EP | claimed |
| US-10077258-B2 | Substituted pyrimidine compounds as phosphatidylinositol 3-kinase delta inhibitor and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2018-09-18 | — | — | US | claimed |
| US-20180037576-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2018-02-08 | — | — | US | claimed |
| EP-3266774-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2018-01-10 | — | — | EP | claimed |
| US-8461072-B2 | Late transition metal catalysts for olefin oligomerizations | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-7994086-B2 | Late transition metal catalysts for olefin oligomerizations | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-08-09 | — | — | US | claimed |
| US-20110092658-A1 | Late Transition Metal Catalysts for Olefin Oligomerizations | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-21 | — | — | US | claimed |
| WO-2009005839-A2 | COMPOUNDS AND METHODS OF USE | THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICE (US) | 2009-01-08 | — | — | WO | claimed |
| US-20050003955-A1 | Late transition metal catalysts for olefin oligomerizations | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-01-06 | — | — | US | claimed |
| US-20040138056-A1 | Late transition metal catalysts for olefin oligomerizations | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-07-15 | — | — | US | claimed |
| WO-2004037869-A2 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-05-06 | — | — | WO | claimed |
| WO-2004037837-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-05-06 | — | — | WO | claimed |
| US-12042479-B2 | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders | INMED PHARMACEUTICALS INC. | 2024-07-23 | — | — | US | disclosed |
| US-20240240048-A1 | POLYROTAXANE HAVING AMINO GROUP | DENKA COMPANY LIMITED (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240238427-A1 | METHODS OF TREATING AN EYE DISORDER | KODIAK SCIENCES INC. | 2024-07-18 | — | — | US | disclosed |
| US-4345071-A | AZIDOALKYL-HETEROCYCLIC AMIDINE INTERMEDIATES | LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) | 1982-08-17 | — | — | US | disclosed |
| US-4259333-A | ANTIBIOTICS, BACTERICIDES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1981-03-31 | — | — | US | disclosed |
| US-4229443-A | Derivatives of penicillanic acid | LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) | 1980-10-21 | — | — | US | disclosed |