Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866453 | 0.92 | CA12 (0.40) | MAPTMAPK1LMNACYP2C9CYP2C19 | |
| SCHEMBL24284449 | 0.91 | NPC1 (0.46) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL17298641 | 0.91 | MAPT (0.39) | MAPTNPC1RAB9AALDH1A1NPBWR1 | |
| SCHEMBL18823083 | 0.87 | MAPT (0.41) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL13536941 | 0.84 | NPC1 (0.44) | MAPTNPC1RAB9ALMNACYP2C9 | |
| SCHEMBL19011462 | 0.83 | MAPT (0.42) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL14116424 | 0.83 | CA12 (0.39) | MAPTMAPK1LMNACA12CA1 | |
| SCHEMBL23951147 | 0.81 | NPC1 (0.46) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL13151640 | 0.81 | MAPT (0.41) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL15457961 | 0.80 | SMN1; SMN2 (0.43) | MAPTNPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285306-B1 | Process for self-repair of insulation material | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2007-10-23 | — | — | US | disclosed |
| US-20070066090-A1 | Wiring board, process for producing the same polyimide film for use in the wiring board, and etchant for use in the process | KANEKA CORPORATION (JP) | 2007-03-22 | — | — | US | disclosed |