Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 20/20 | 0.85 |
| ▸ | TBXA2R | P21731 | 19/20 | 0.85 |
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449868 | 0.92 | PTGDR (1.00) | PTGDRTBXA2RPDE2A | |
| SCHEMBL1042323 | 0.92 | PTGDR (1.00) | PTGDRTBXA2RPDE2A | |
| SCHEMBL990454 | 0.92 | TBXA2R (1.00) | PTGDRTBXA2RPDE2A | |
| SCHEMBL3872881 | 0.91 | PTGDR (1.00) | PTGDRTBXA2RPDE2A | |
| SCHEMBL991127 | 0.91 | TBXA2R (1.00) | PTGDRTBXA2RPDE2A | |
| SCHEMBL991078 | 0.89 | PTGDR (1.00) | PTGDRTBXA2RPDE2A | |
| SCHEMBL990560 | 0.87 | TBXA2R (0.84) | PTGDRTBXA2RPDE2A | |
| SCHEMBL991162 | 0.87 | TBXA2R (1.00) | PTGDRTBXA2R | |
| SCHEMBL22722578 | 0.87 | TBXA2R (0.90) | PTGDRTBXA2RPDE2A | |
| SCHEMBL991147 | 0.82 | PTGDR (1.00) | PTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120575-A2 | NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2007-10-25 | — | — | WO | disclosed |