⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618618 | 1.00 | — | — | |
| SCHEMBL664383 | 0.82 | — | — | |
| SCHEMBL10347089 | 0.82 | — | — | |
| SCHEMBL664382 | 0.82 | — | — | |
| SCHEMBL28752347 | 0.78 | — | — | |
| SCHEMBL8770964 | 0.67 | — | — | |
| Ethylene Glycol SCHEMBL1765971 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL129389 | 0.64 | — | — | |
| SCHEMBL913391 | 0.64 | — | — | |
| SCHEMBL283405 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444085-B1 | Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer | UNIV CALIFORNIA (US) | 2015-03-18 | — | — | EP | disclosed |
| EP-2397469-B1 | Diarylhydantoin compounds | UNIV CALIFORNIA (US) | 2014-12-31 | — | — | EP | disclosed |
| EP-2561871-A1 | Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer | The Regents of The University of California (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2007111948-A2 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-04 | — | — | WO | disclosed |