Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849891 | 0.84 | TAAR1 (0.58) | TAAR1 | |
| SCHEMBL13849941 | 0.84 | TAAR1 (0.58) | TAAR1 | |
| SCHEMBL14402407 | 0.84 | TAAR1 (0.58) | TAAR1 | |
| SCHEMBL15178077 | 0.83 | TAAR1 (0.45) | TAAR1CETP | |
| SCHEMBL1417063 | 0.83 | TAAR1 (0.45) | TAAR1DHFRACHECETPP2RX3 | |
| SCHEMBL1416802 | 0.82 | TAAR1 (0.50) | TAAR1DHFRACHECETPP2RX3 | |
| SCHEMBL9935171 | 0.82 | TAAR1 (0.50) | TAAR1DHFRACHECETPP2RX3 | |
| SCHEMBL14402644 | 0.82 | CETP (0.55) | CETPPPARGPPARA | |
| SCHEMBL13850049 | 0.82 | CETP (0.55) | CETPPPARGPPARA | |
| SCHEMBL14402689 | 0.81 | CETP (0.41) | TAAR1CETPPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |