SCHEMBL1440372

SCHEMBL1440372

[C]#CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6321542 0.67
SCHEMBL1457298 0.60
SCHEMBL6913000 0.59
SCHEMBL10550667 0.59
SCHEMBL20317 0.59
SCHEMBL50067 0.59
SCHEMBL139417 0.56
Acrylonitrile SCHEMBL1331891 0.56
SCHEMBL14860612 0.56
SCHEMBL5533285 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150011517-A1 LUPANE TRITERPENOID DERIVATIVES AND PHARMACEUTICAL USE THEREOF JIANGXI QINGFENG PHARMACEUTICAL INC. (CN) 2015-01-08 US claimed
EP-2812343-A1 LUPANE TRITERPENOID DERIVATIVES AND PHARMACEUTICAL USE THEREOF Jiangxi Qingfeng Pharmaceutical Inc. (CN) 2014-12-17 EP claimed
EP-2176222-B1 NOVEL HERBICIDES SYNGENTA LTD (GB) 2014-11-05 EP claimed
WO-2013117137-A1 LUPANE TRITERPENOID DERIVATIVES AND PHARMACEUTICAL USE THEREOF JIANGXI QINGFENG PHARMACEUTICAL INC. (CN) 2013-08-15 WO claimed
US-7799762-B2 Acyl pseudodipeptides which carry a functionalised auxialiary arm OM PHARMA (CH) 2010-09-21 US claimed
US-7057027-B2 Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines ISIS PHARMACEUTICALS, INC. (US) 2006-06-06 US claimed
JP-3739785-B2 2006-01-25 JP claimed
US-20050192232-A1 Novel acyl-dipeptide-like compounds bearing an accessory functional side chain spacer, a method for preparing the same and pharmaceutical compositions containing such products OM PHARMA (CH) 2005-09-01 US claimed
US-20050118605-A9 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation ISIS PHARMACEUTICALS, INC. 2005-06-02 US claimed
US-6875593-B2 Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines ISIS PHARMACEUTICALS, INC. (US) 2005-04-05 US claimed
EP-0929519-A1 $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS PHARMACIA &amp; UPJOHN COMPANY (US) 1999-07-21 EP claimed
US-5847153-A β-sulfonyl hydroxamic acids PHARMACIA & UPJOHN COMPANY (US) 1998-12-08 US claimed
WO-1998013340-A1 β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 1998-04-02 WO claimed
US-5645985-A USED FOR DIAGNOSIS TO DETECT VIRUSES OR DISEASED CONDITIONS GILEAD SCIENCES, INC. (US) 1997-07-08 US claimed
EP-0637965-A4 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES. GILEAD SCIENCES INC (US) 1996-01-24 EP claimed
US-5484908-A URACIL OR CYTOSINE DERIVATIVES, DETECTION OF DNA SEQUENCES GILEAD SCIENCES, INC. (US) 1996-01-16 US claimed
EP-0637965-A1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES GILEAD SCIENCES, INC. (US) 1995-02-15 EP claimed
WO-1993010820-A1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES GILEAD SCIENCES, INC. (US) 1993-06-10 WO claimed
US-5153199-A Pyridyl cyclopropane amide derivates for treating infections of plants IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-10-06 US claimed
EP-0434357-A2 Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-26 EP claimed