Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | GFER | P55789 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400143 | 0.91 | KMT2A (0.46) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14404108 | 0.91 | MAPT (0.53) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14399837 | 0.90 | KMT2A (0.50) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14404050 | 0.89 | MAPT (0.49) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14404095 | 0.86 | MAPT (0.44) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14404093 | 0.85 | PPARG (0.42) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14404094 | 0.82 | GAA (0.42) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14399687 | 0.82 | KMT2A (0.43) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14400139 | 0.82 | KMT2A (0.50) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14400025 | 0.81 | KMT2A (0.51) | MAPTMEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116314-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (US) | 2007-10-18 | — | — | WO | disclosed |