Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12000750 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL16661755 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL13696395 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL12000749 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL15481876 | 0.73 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL13391794 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL10142408 | 0.67 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1TDP1TSHRKDM4E | |
| Water SCHEMBL11082954 | 0.67 | SMN1; SMN2 (0.96) | SMN1; SMN2ALDH1A1TDP1TSHRPDK1 | |
| Water SCHEMBL27710978 | 0.67 | SMN1; SMN2 (0.96) | SMN1; SMN2ALDH1A1TDP1TSHRPDK1 | |
| SCHEMBL13497251 | 0.66 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1TDP1TSHRPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344132-B2 | Methods for the preparation of 9-deazapurine derivatives | BioCryst Pharmaceticals, Inc. (US) | 2013-01-01 | — | — | US | disclosed |