SCHEMBL14408693

SCHEMBL14408693

CCS(=O)(=O)NCCCCCNc1nc2c(s1)CCCc1ccc(F)cc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1594047 0.92 NPY5R (1.00) NPY5R
SCHEMBL1594283 0.91 NPY5R (0.98) NPY5R
SCHEMBL14408700 0.90 NPY5R (0.82) NPY5R
SCHEMBL1594080 0.90 NPY5R (0.82) NPY5R
SCHEMBL14408683 0.90 NPY5R (1.00) NPY5R
SCHEMBL14408692 0.90 NPY5R (1.00) NPY5R
SCHEMBL1593534 0.90 NPY5R (0.81) NPY5R
SCHEMBL14408618 0.89 NPY5R (0.80) NPY5R
SCHEMBL14408622 0.89 NPY5R (0.80) NPY5R
SCHEMBL14408719 0.89 NPY5R (1.00) NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7273880-B2 Selective NPY (Y5) antagonists H. LUNBECK A/S (DK) 2007-09-25 US disclosed
US-7273880-B2 Selective NPY (Y5) antagonists H. LUNBECK A/S (DK) 2007-09-25 US disclosed