SCHEMBL1440930

SCHEMBL1440930

[O]C12CCCC(C1)C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154813 0.88
SCHEMBL155496 0.83
SCHEMBL157034 0.83
SCHEMBL2288424 0.81
SCHEMBL155699 0.77
SCHEMBL151703 0.76
SCHEMBL25418462 0.69
SCHEMBL155348 0.69
SCHEMBL6260329 0.65
SCHEMBL6260334 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11661410-B2 Tricyclic compounds as histone methyltransferase inhibitors GLOBAL BLOOD THERAPEUTICS, INC. (US) 2023-05-30 US disclosed
US-11584734-B2 Tricyclic compounds as histone methyltransferase inhibitors GLOBAL BLOOD THERAPEUTICS, INC. (US) 2023-02-21 US disclosed
US-20230002351-A1 TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS GLOBAL BLOOD THERAPEUTICS, INC. 2023-01-05 US disclosed
US-20200361896-A1 TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS GLOBAL BLOOD THERAPEUTICS, INC. 2020-11-19 US disclosed
EP-3668863-A1 TRICYCLIC COMPOUNDS AS HISTONE METHYL-TRANSFERASE INHIBITORS Global Blood Therapeutics, Inc. (US) 2020-06-24 EP disclosed
WO-2019036377-A1 TRICYCLIC COMPOUNDS AS HISTONE METHYL-TRANSFERASE INHIBITORS GLOBAL BLOOD THERAPEUTICS, INC. (US) 2019-02-21 WO disclosed
WO-2019036384-A1 TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS GLOBAL BLOOD THERAPEUTICS, INC. (US) 2019-02-21 WO disclosed
US-9944623-B2 Sterically hindered amine stabilizer BASF SE (DE) 2018-04-17 US disclosed
EP-2475655-B1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2017-10-11 EP disclosed
US-20160347736-A1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2016-12-01 US disclosed
US-9464070-B2 Sterically hindered amine stabilizer BASF SE (DE) 2016-10-11 US disclosed
US-8895647-B2 Sterically hindered amine stabilizer BASF SE (DE) 2014-11-25 US disclosed
US-20140336313-A1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2014-11-13 US disclosed
US-20120232197-A1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2012-09-13 US disclosed
EP-2475655-A1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2012-07-18 EP disclosed
WO-2011029744-A1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2011-03-17 WO disclosed