Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223528 | 1.00 | HRH3 (0.72) | HRH3KCNH2PTGS2ALDH1A1NPC1 | |
| SCHEMBL5221321 | 0.98 | HRH3 (0.75) | HRH3KCNH2PTGS2ALDH1A1NPC1 | |
| SCHEMBL14409312 | 0.98 | HRH3 (0.75) | HRH3KCNH2PTGS2ALDH1A1NPC1 | |
| SCHEMBL5224172 | 0.97 | HRH3 (0.74) | HRH3KCNH2PTGS2ALDH1A1NPC1 | |
| SCHEMBL14409347 | 0.97 | HRH3 (0.74) | HRH3KCNH2PTGS2ALDH1A1NPC1 | |
| SCHEMBL5221610 | 0.86 | HRH3 (0.71) | HRH3KCNH2PTGS2KMT2A | |
| SCHEMBL5221600 | 0.86 | HRH3 (0.71) | HRH3KCNH2PTGS2KMT2A | |
| SCHEMBL5221616 | 0.86 | HRH3 (0.71) | HRH3KCNH2PTGS2KMT2A | |
| SCHEMBL5958347 | 0.85 | HRH3 (0.70) | HRH3KCNH2PTGS2ALDH1A1GAA | |
| SCHEMBL5219293 | 0.85 | HRH3 (0.70) | HRH3KCNH2PTGS2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474419-B1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK AS (DK) | 2007-09-05 | — | — | EP | disclosed |