Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 3/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216540 | 1.00 | HRH3 (1.00) | HRH3KCNH2OPRD1KMT2ACYP1A2 | |
| SCHEMBL5218586 | 0.99 | HRH3 (0.98) | HRH3KCNH2OPRD1KMT2A | |
| SCHEMBL14409481 | 0.99 | HRH3 (0.98) | HRH3KCNH2OPRD1KMT2A | |
| SCHEMBL14409586 | 0.98 | HRH3 (0.96) | HRH3KCNH2OPRD1KMT2A | |
| SCHEMBL5220599 | 0.98 | HRH3 (0.96) | HRH3KCNH2OPRD1KMT2A | |
| SCHEMBL14409442 | 0.89 | HRH3 (0.80) | HRH3KCNH2OPRD1KMT2ACYP1A2 | |
| SCHEMBL5217787 | 0.89 | HRH3 (0.80) | HRH3KCNH2OPRD1KMT2ACYP1A2 | |
| SCHEMBL14409420 | 0.87 | HRH3 (0.78) | HRH3KCNH2OPRD1KMT2A | |
| SCHEMBL5220654 | 0.87 | HRH3 (0.78) | HRH3KCNH2OPRD1KMT2A | |
| SCHEMBL14409440 | 0.87 | HRH3 (0.77) | HRH3KCNH2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474419-B1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK AS (DK) | 2007-09-05 | — | — | EP | disclosed |