SCHEMBL14410885

SCHEMBL14410885

B[C@](C)(CC)CC(C)(Cl)CC

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6917772 0.73 TSHR (0.35) TSHRTDP1
SCHEMBL665337 0.71
SCHEMBL12208874 0.71
SCHEMBL27571796 0.71
SCHEMBL9974261 0.69 TSHR (0.32) TSHRTDP1
Hydrochloric Acid SCHEMBL28406991 0.68
SCHEMBL28496863 0.68
SCHEMBL1313484 0.68
SCHEMBL8474207 0.67 TSHR (0.30) TSHRTDP1
SCHEMBL5385540 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829875-A1 Pyrazole derivatives as sigma receptor inhibitors LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-09-05 EP disclosed