Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 0.54 |
| ▸ | MERTK | Q12866 | 20/20 | 0.54 |
| ▸ | TYRO3 | Q06418 | 15/20 | 0.54 |
| ▸ | MET | P08581 | 19/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14411988 | 0.91 | AXL (0.54) | AXLMERTKTYRO3MET | |
| SCHEMBL3109241 | 0.88 | AXL (0.69) | AXLMERTKTYRO3MET | |
| SCHEMBL14412010 | 0.85 | AXL (0.53) | AXLMERTKTYRO3MET | |
| SCHEMBL14411901 | 0.80 | AXL (0.67) | AXLMERTKTYRO3MET | |
| SCHEMBL14411941 | 0.80 | AXL (0.64) | AXLMERTKTYRO3MET | |
| SCHEMBL3109010 | 0.79 | AXL (0.69) | AXLMERTKTYRO3MET | |
| SCHEMBL3109001 | 0.79 | AXL (0.69) | AXLMERTKTYRO3MET | |
| SCHEMBL14411847 | 0.79 | AXL (0.64) | AXLMERTKTYRO3MET | |
| SCHEMBL13905992 | 0.78 | AXL (0.55) | AXLMERTKTYRO3MET | |
| SCHEMBL14411987 | 0.76 | AXL (0.57) | AXLMERTKTYRO3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007103308-A2 | HETEROBICYCLIC PYRAZOLE COMPOUNDS AND METHODS OF USE | ARRAY BIOPHARMA INC. (US) | 2007-09-13 | — | — | WO | disclosed |