Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.68 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13762543 | 0.93 | MAPK14 (0.65) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL14412679 | 0.90 | MAPK14 (0.62) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL13755692 | 0.90 | MAPK14 (0.63) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL13755694 | 0.90 | MAPK14 (0.63) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL14412393 | 0.89 | MAPK14 (0.57) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL14417142 | 0.88 | MAPK14 (0.63) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL13755528 | 0.88 | MAPK14 (0.62) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL13755510 | 0.88 | MAPK14 (0.62) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL13755736 | 0.87 | MAPK14 (0.60) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL13755407 | 0.87 | MAPK14 (0.62) | MAPK14MAPK11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007103839-A2 | PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-09-13 | — | — | WO | disclosed |