Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DHCR24 | Q15392 | 4/20 | 0.41 |
| ▸ | OSBP | P22059 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335972 | 0.81 | USP2 (0.53) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL14412606 | 0.79 | CYP3A4 (0.59) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL14412597 | 0.79 | CYP3A4 (0.59) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL12869788 | 0.79 | CYP3A4 (0.59) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL12869830 | 0.79 | CYP3A4 (0.59) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL5341638 | 0.77 | USP2 (0.49) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL5346604 | 0.77 | USP2 (0.49) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL14412747 | 0.74 | MEN1 (0.49) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL14412602 | 0.74 | MEN1 (0.49) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL14412743 | 0.74 | MEN1 (0.49) | MEN1KMT2AALDH1A1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007103508-A2 | LIGANDS FOR NEMATODE NUCLEAR RECEPTORS AND USES THEREOF | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2007-09-13 | — | — | WO | disclosed |