Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 20/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | CYP2J2 | P51589 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873458 | 0.87 | EPHX2 (0.77) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL14413553 | 0.82 | EPHX2 (0.58) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL14413296 | 0.81 | EPHX2 (0.81) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL13873466 | 0.79 | EPHX2 (0.78) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL14413377 | 0.78 | EPHX2 (0.90) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL13873488 | 0.78 | EPHX2 (0.62) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL13873369 | 0.77 | EPHX2 (1.00) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL25218628 | 0.76 | NPSR1 (0.51) | EPHX2CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL14413613 | 0.75 | HRH3 (0.70) | EPHX2 | |
| SCHEMBL13873356 | 0.75 | EPHX2 (1.00) | EPHX2CYP2C9CYP2J2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |