Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873419 | 0.85 | EPHX2 (1.00) | EPHX2NAMPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL8361624 | 0.83 | SMN1; SMN2 (0.97) | EPHX2SMN1; SMN2MAPTGAABLM | |
| SCHEMBL4559572 | 0.83 | SMN1; SMN2 (0.91) | SMN1; SMN2MAPTGAABLMALDH1A1 | |
| SCHEMBL5195426 | 0.82 | SMN1; SMN2 (1.00) | EPHX2SMN1; SMN2MAPTGAABLM | |
| SCHEMBL23288503 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTGAABLMALDH1A1 | |
| SCHEMBL28869329 | 0.80 | MAPT (1.00) | SMN1; SMN2MAPTBLMALDH1A1RAB9A | |
| SCHEMBL14413881 | 0.80 | GAA (0.67) | EPHX2SMN1; SMN2MAPTGAAHPGD | |
| SCHEMBL6716470 | 0.79 | MAPT (0.65) | SMN1; SMN2MAPTGAABLMALDH1A1 | |
| SCHEMBL20796549 | 0.78 | MAPT (0.77) | EPHX2SMN1; SMN2MAPTGAABLM | |
| SCHEMBL1576169 | 0.77 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTGAABLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106706-A1 | CYCLIC UREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS EFFECTIVE FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |