Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629197 | 0.93 | ADORA2A (0.67) | ADORA2AADORA1ADORA3 | |
| SCHEMBL12629176 | 0.93 | ADORA2A (0.67) | ADORA2AADORA1ADORA3 | |
| SCHEMBL14427842 | 0.92 | ADORA2A (0.66) | ADORA2AADORA1ADORA3 | |
| SCHEMBL15425652 | 0.87 | ADORA2A (0.76) | ADORA2AADORA1ADORA3 | |
| SCHEMBL15426675 | 0.87 | ADORA2A (0.76) | ADORA2AADORA1ADORA3 | |
| SCHEMBL24436981 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL2503875 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL1864206 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL22452094 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL12629177 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271157-B2 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. (US) | 2007-09-18 | — | — | US | disclosed |