⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12050301 | 0.73 | — | — | |
| SCHEMBL14601756 | 0.72 | ATM (0.31) | — | |
| SCHEMBL14156694 | 0.71 | — | — | |
| SCHEMBL6354239 | 0.69 | — | — | |
| SCHEMBL14156696 | 0.69 | — | — | |
| SCHEMBL17414386 | 0.68 | — | — | |
| SCHEMBL17414379 | 0.67 | GAA (0.36) | — | |
| SCHEMBL18779683 | 0.66 | — | — | |
| SCHEMBL18372273 | 0.65 | AKR1C3 (0.37) | — | |
| SCHEMBL10073196 | 0.65 | BIRC2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |