Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490171 | 0.88 | KMT2A (0.54) | ALDH1A1CES2CES1CYP1A2CYP3A4 | |
| SCHEMBL6656194 | 0.88 | KMT2A (0.54) | ALDH1A1CES2CES1CYP1A2CYP3A4 | |
| SCHEMBL6656199 | 0.88 | KMT2A (0.54) | ALDH1A1CES2CES1CYP1A2CYP3A4 | |
| SCHEMBL563406 | 0.88 | TP53 (0.52) | ALDH1A1CES2CES1MEN1KMT2A | |
| SCHEMBL11426055 | 0.87 | MAPT (0.56) | ALDH1A1CES2CES1MEN1KMT2A | |
| SCHEMBL7391093 | 0.86 | MAPT (0.52) | ALDH1A1CES2CES1CYP1A2CYP3A4 | |
| SCHEMBL7391094 | 0.86 | MAPT (0.52) | ALDH1A1CES2CES1CYP1A2CYP3A4 | |
| SCHEMBL7391091 | 0.86 | MAPT (0.52) | ALDH1A1CES2CES1CYP1A2CYP3A4 | |
| SCHEMBL5754032 | 0.85 | TP53 (0.58) | ALDH1A1CES2CES1CYP1A2CYP3A4 | |
| SCHEMBL5754033 | 0.85 | TP53 (0.58) | ALDH1A1CES2CES1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070218486-A1 | Immunoassays, Haptens, Immunogens and Antibodies for Anti-HIV Therapeutics | ARK DIAGNOSTICS, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070218486-A1 | Immunoassays, Haptens, Immunogens and Antibodies for Anti-HIV Therapeutics | ARK DIAGNOSTICS, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| WO-2007103740-A2 | IMMUNOASSAYS, HAPTENS, IMMUNOGENS AND ANTIBODIES FOR ANTI-HIV THERAPEUTICS | ARK DIAGNOSTICS (US) | 2007-09-13 | — | — | WO | disclosed |