Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | EED | O75530 | 3/20 | 0.51 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.51 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417705 | 0.84 | IDO1 (0.62) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL14417745 | 0.73 | IDO1 (0.55) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL14417704 | 0.72 | MEN1 (0.50) | IDO1MEN1CES2ALDH1A1HPGD | |
| Tanshinone Iia Sulfonic Acid SCHEMBL14417738 | 0.72 | MEN1 (0.80) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL14417741 | 0.72 | MEN1 (0.67) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL28411969 | 0.72 | MEN1 (0.67) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL14417726 | 0.70 | MEN1 (0.64) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL14417881 | 0.70 | MEN1 (0.80) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL14417699 | 0.69 | MEN1 (0.63) | IDO1MEN1CES2ALDH1A1HPGD | |
| SCHEMBL28841602 | 0.69 | MEN1 (0.63) | IDO1MEN1CES2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | SAVIPU PHARMACEUTICALS (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | NFKBIA, EDNRA, EDNRB | IDO1 1339/4885MEN1 3639/4885CES2 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.