Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | CES2 | O00748 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.52 |
| ▸ | EED | O75530 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417748 | 0.91 | MEN1 (0.58) | MEN1CES2ALDH1A1HPGDKMT2A | |
| SCHEMBL14417741 | 0.80 | MEN1 (0.67) | MEN1CES2ALDH1A1HPGDKMT2A | |
| SCHEMBL28411969 | 0.80 | MEN1 (0.67) | MEN1CES2ALDH1A1HPGDKMT2A | |
| SCHEMBL14417744 | 0.80 | MEN1 (0.51) | MEN1CES2ALDH1A1HPGDKMT2A | |
| SCHEMBL14417726 | 0.79 | MEN1 (0.64) | MEN1CES2ALDH1A1HPGDKMT2A | |
| SCHEMBL14417699 | 0.78 | MEN1 (0.63) | MEN1CES2ALDH1A1HPGDKMT2A | |
| Tanshinone Iia Sulfonic Acid SCHEMBL30094475 | 0.76 | MEN1 (1.00) | MEN1CES2ALDH1A1HPGDKMT2A | |
| Tanshinone Iia Sulfonic Acid SCHEMBL28665868 | 0.76 | MEN1 (1.00) | MEN1CES2ALDH1A1HPGDKMT2A | |
| SCHEMBL14417731 | 0.75 | NAMPT (0.61) | MEN1CES2ALDH1A1HPGDKMT2A | |
| Tanshinone Iia Sulfonic Acid SCHEMBL14417738 | 0.74 | MEN1 (0.80) | MEN1CES2ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | SAVIPU PHARMACEUTICALS (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | NFKBIA, EDNRA, EDNRB | MEN1 3639/4885CES2 4449/4885ALDH1A1 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.