Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813964 | 0.90 | KDM4E (0.54) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL814177 | 0.79 | KDM4E (0.56) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL813793 | 0.75 | KDM4E (0.66) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL813671 | 0.75 | KDM4E (0.57) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL813863 | 0.71 | KDM4E (0.56) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL813879 | 0.70 | KDM4E (0.59) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL814532 | 0.70 | GAA (0.57) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL12460834 | 0.70 | KDM4E (0.72) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL814014 | 0.69 | KDM4E (0.60) | GAAKDM4ETP53ALOX15TSHR | |
| SCHEMBL5212990 | 0.69 | KDM4E (1.00) | GAAKDM4ETP53ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |