Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.54 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | HTT | P42858 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419570 | 0.93 | P2RX1 (0.60) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL14419305 | 0.88 | CA1 (0.60) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL14419662 | 0.86 | TMPRSS4 (0.50) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL14419660 | 0.84 | KMT2A (0.54) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL27380941 | 0.83 | HTT (0.68) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL14419290 | 0.83 | KMT2A (0.70) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL14419569 | 0.81 | CA1 (0.51) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL14419573 | 0.80 | POLB (0.57) | KMT2AHTTLMNAMEN1MAPT | |
| SCHEMBL11849601 | 0.80 | MAPT (0.48) | P2RX1TMPRSS4KDM4EKMT2AHTT | |
| SCHEMBL9779330 | 0.79 | CA1 (0.62) | P2RX1TMPRSS4KDM4EKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |