Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775961 | 0.89 | PPARD (0.53) | PPARDPPARAPPARGAPEX1KDM4E | |
| SCHEMBL1776492 | 0.89 | KDM4E (0.56) | PPARDPPARAPPARGAPEX1KDM4E | |
| SCHEMBL1776443 | 0.88 | PPARD (0.51) | PPARDPPARAPPARGAPEX1KDM4E | |
| SCHEMBL1744313 | 0.87 | PPARD (0.52) | PPARDPPARAPPARGAPEX1KDM4E | |
| SCHEMBL1744311 | 0.87 | PPARD (0.52) | PPARDPPARAPPARGAPEX1KDM4E | |
| SCHEMBL1744314 | 0.87 | PPARD (0.52) | PPARDPPARAPPARGAPEX1KDM4E | |
| SCHEMBL1777106 | 0.87 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL1775862 | 0.86 | PPARD (0.59) | PPARDPPARAPPARGAPEX1KDM4E | |
| SCHEMBL1777987 | 0.82 | PPARD (0.46) | PPARDPPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL1778482 | 0.81 | KDM4E (0.52) | PPARDPPARAPPARGKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007101864-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS, LLC (US) | 2007-09-13 | — | — | WO | disclosed |