Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CCR5 | P51681 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420118 | 0.90 | CCR1 (0.53) | CCR1CHRM2CCR5HRH1TBXA2R | |
| SCHEMBL14579626 | 0.90 | CCR1 (0.53) | CCR1CHRM2CCR5HRH1TBXA2R | |
| SCHEMBL16312659 | 0.89 | CCR1 (0.51) | CCR1CHRM2CCR5HRH1TBXA2R | |
| SCHEMBL14579630 | 0.89 | CCR1 (0.48) | CCR1CHRM2CCR5HRH1TBXA2R | |
| SCHEMBL13824432 | 0.89 | CCR1 (0.48) | CCR1CHRM2CCR5HRH1TBXA2R | |
| SCHEMBL13824440 | 0.87 | CCR1 (0.52) | CCR1CHRM2CCR5HRH1TBXA2R | |
| SCHEMBL12121845 | 0.86 | CCR1 (0.51) | CCR1CHRM2CCR5HRH1TBXA2R | |
| SCHEMBL13824434 | 0.86 | CCR1 (0.48) | CCR1CHRM2CCR5HRH1 | |
| SCHEMBL10287557 | 0.86 | CCR1 (0.49) | CCR1CHRM2CCR5HRH1 | |
| SCHEMBL16312643 | 0.85 | CCR1 (0.48) | CCR1CHRM2CCR5HRH1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271176-B2 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-09-18 | — | — | US | disclosed |