Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13292243 | 0.88 | CCR1 (0.47) | CCR1CHRM2CCR5TBXA2RTBXAS1 | |
| SCHEMBL653939 | 0.78 | CCR1 (0.59) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL653940 | 0.78 | CCR1 (0.59) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL13804506 | 0.77 | CCR1 (0.50) | CCR1CHRM2CCR5TBXA2RTBXAS1 | |
| SCHEMBL654072 | 0.77 | CCR1 (0.50) | CCR1CHRM2CCR5TBXA2RTBXAS1 | |
| SCHEMBL654071 | 0.77 | CCR1 (0.50) | CCR1CHRM2CCR5TBXA2RTBXAS1 | |
| SCHEMBL13616996 | 0.75 | CCR1 (0.55) | CCR1CHRM2CCR5 | |
| SCHEMBL12121902 | 0.74 | CCR1 (0.62) | CCR1CHRM2CCR5 | |
| SCHEMBL655908 | 0.73 | CCR1 (0.66) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL655909 | 0.73 | CCR1 (0.66) | CCR1CHRM2CCR5TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271176-B2 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-09-18 | — | — | US | disclosed |