Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.77 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.77 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930805 | 0.88 | TRPV1 (0.82) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL29386030 | 0.87 | TRPV1 (1.00) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL14423739 | 0.87 | TRPV1 (0.77) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL13377930 | 0.87 | TRPV1 (0.77) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL1269620 | 0.87 | TRPV1 (1.00) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL14423741 | 0.84 | PANK3 (0.72) | TRPV1 | |
| SCHEMBL14423771 | 0.79 | TRPV1 (0.86) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL14423743 | 0.78 | TRPV1 (1.00) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL14423737 | 0.76 | TRPV1 (0.80) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL8336071 | 0.76 | TRPV1 (1.00) | TRPV1TRPA1KCNH2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256193-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2007-08-14 | — | — | US | disclosed |
| US-7256193-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2007-08-14 | — | — | US | disclosed |