Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654199 | 0.86 | GCK (0.41) | GCKKCNH2 | |
| SCHEMBL2654202 | 0.86 | GCK (0.41) | GCKKCNH2 | |
| SCHEMBL2666203 | 0.86 | GCK (0.50) | GRIN2BGCKBCL2 | |
| SCHEMBL2654302 | 0.83 | GCK (0.43) | GCKKCNH2 | |
| SCHEMBL2654305 | 0.83 | GCK (0.43) | GCKKCNH2 | |
| SCHEMBL2666332 | 0.82 | GRIN2B (0.46) | GRIN2BGCKBCL2 | |
| SCHEMBL5392707 | 0.82 | GRIN2B (0.46) | GRIN2BGCKBCL2 | |
| SCHEMBL2653089 | 0.80 | GCK (0.42) | GCKKCNH2 | |
| SCHEMBL2653087 | 0.80 | GCK (0.42) | GCKKCNH2 | |
| SCHEMBL2655251 | 0.80 | GCK (0.41) | GCKKCNH2FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262196-B2 | Tri(cyclo) substituted amide glucokinase activator compounds | PROSIDION LIMITED (GB) | 2007-08-28 | — | — | US | disclosed |
| US-7262196-B2 | Tri(cyclo) substituted amide glucokinase activator compounds | PROSIDION LIMITED (GB) | 2007-08-28 | — | — | US | disclosed |