Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | GCK | P35557 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654461 | 0.89 | GCK (0.46) | GCK | |
| SCHEMBL2654465 | 0.89 | GCK (0.46) | GCK | |
| SCHEMBL2653794 | 0.85 | GCK (0.64) | SMN1; SMN2GCKGAAMEN1KMT2A | |
| SCHEMBL2653788 | 0.85 | GCK (0.64) | SMN1; SMN2GCKGAAMEN1KMT2A | |
| SCHEMBL2646460 | 0.77 | GCK (0.59) | GCKKMT2A | |
| SCHEMBL2646462 | 0.77 | GCK (0.59) | GCKKMT2A | |
| SCHEMBL2645565 | 0.77 | GCK (0.58) | GCKKMT2ACLK1 | |
| SCHEMBL2645561 | 0.77 | GCK (0.58) | GCKKMT2ACLK1 | |
| SCHEMBL2021805 | 0.77 | GCK (0.53) | SMN1; SMN2GCKRAB9ANPC1GAA | |
| SCHEMBL1024394 | 0.77 | GCK (0.53) | SMN1; SMN2GCKRAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262196-B2 | Tri(cyclo) substituted amide glucokinase activator compounds | PROSIDION LIMITED (GB) | 2007-08-28 | — | — | US | disclosed |