SCHEMBL14425633

SCHEMBL14425633

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5cccc(-n6c7ccccc7c7ccccc76)c5)c4)c3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.47
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP19A1 P11511 1/20 0.40
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
PDE10A Q9Y233 1/20 0.38
KMT2A Q03164 5/20 0.38
MEN1 O00255 4/20 0.38
RAB9A P51151 1/20 0.38
TET2 Q6N021 1/20 0.36
TET1 Q8NFU7 1/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 2/20 0.36
ACHE P22303 1/20 0.36
FAAH O00519 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14425637 1.00 ATM (0.47) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539727 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539748 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539756 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539745 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539765 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539752 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539739 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL11992460 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2
SCHEMBL17539743 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP19A1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed