SCHEMBL14425852

SCHEMBL14425852

c1ccc(-c2cccc(-c3ccc(-c4ccncc4)cc3)c2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.54
CYP2A6 P11509 1/20 0.52
NOTUM Q6P988 1/20 0.50
HRH3 Q9Y5N1 1/20 0.47
KDM4E B2RXH2 4/20 0.46
LMNA P02545 3/20 0.46
CCR1 P32246 2/20 0.46
CCR5 P51681 2/20 0.46
CCR8 P51685 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
METAP1 P53582 1/20 0.46
BLM P54132 1/20 0.46
HIF1A Q16665 1/20 0.46
DOHH Q9BU89 1/20 0.46
P4HTM Q9NXG6 1/20 0.46
TP53 P04637 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 2/20 0.46
PKM P14618 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13859467 0.98 GRM5 (0.55) GRM5CYP2A6NOTUMHRH3KDM4E
SCHEMBL17264895 0.96 GRM5 (0.54) GRM5CYP2A6NOTUMHRH3KDM4E
SCHEMBL14425851 0.96 GRM5 (0.54) GRM5CYP2A6NOTUMHRH3KDM4E
SCHEMBL16356779 0.96 GRM5 (0.54) GRM5CYP2A6NOTUMHRH3KDM4E
SCHEMBL19238780 0.95 GRM5 (0.50) GRM5CYP2A6NOTUMHRH3KDM4E
SCHEMBL18650152 0.91 NOTUM (0.54) GRM5CYP2A6NOTUMHRH3KDM4E
SCHEMBL17945604 0.91 GRM5 (0.47) GRM5CYP2A6NOTUMHRH3KDM4E
SCHEMBL14425486 0.90 KDM4E (0.52) GRM5CYP2A6HRH3KDM4ELMNA
SCHEMBL26499340 0.90 KDM4E (0.52) GRM5CYP2A6HRH3KDM4ELMNA
SCHEMBL21173056 0.90 KDM4E (0.56) GRM5CYP2A6HRH3KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed