SCHEMBL14426136

SCHEMBL14426136

c1ccc(-c2cc(-c3ccc(-c4cc(-c5ccccc5)cc(-c5cc(-n6c7ccccc7c7ccccc76)nc(-n6c7ccccc7c7ccccc76)c5)c4)cc3)cc(-c3cc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)c3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 4/20 0.36
HPGD P15428 2/20 0.36
FGFR1 P11362 1/20 0.35
DYRK3 O43781 1/20 0.35
CLK1 P49759 1/20 0.35
CLK2 P49760 1/20 0.35
CLK3 P49761 1/20 0.35
GSK3B P49841 1/20 0.35
CDK5 Q00535 1/20 0.35
DYRK1A Q13627 1/20 0.35
CDK5R1 Q15078 1/20 0.35
DYRK2 Q92630 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
DHODH Q02127 1/20 0.35
KMT2A Q03164 6/20 0.35
MEN1 O00255 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14426139 1.00 KDM4E (0.44) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL14426137 1.00 KDM4E (0.44) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL14426140 1.00 KDM4E (0.44) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL24609446 0.98 KDM4E (0.45) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL11992467 0.96 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL30232779 0.96 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL14426132 0.95 KDM4E (0.38) KDM4EL3MBTL1ATMFGFR1DYRK3
SCHEMBL14426134 0.95 KDM4E (0.38) KDM4EL3MBTL1ATMFGFR1DYRK3
SCHEMBL14426133 0.95 KDM4E (0.38) KDM4EL3MBTL1ATMFGFR1DYRK3
SCHEMBL14426130 0.95 KDM4E (0.38) KDM4EL3MBTL1ATMFGFR1DYRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed