SCHEMBL14426201

SCHEMBL14426201

c1cc(-c2ccc(-c3nc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)n3)cc2)cc(-c2cccc(-c3nc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)n3)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
ATM Q13315 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GP6 Q9HCN6 1/20 0.36
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
LMNA P02545 2/20 0.35
USP2 O75604 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
NTSR1 P30989 1/20 0.34
ABCG2 Q9UNQ0 3/20 0.34
ABCB1 P08183 1/20 0.34
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14426194 1.00 KDM4E (0.36) KDM4EATML3MBTL1GP6MEN1
SCHEMBL14426191 1.00 KDM4E (0.36) KDM4EATML3MBTL1GP6MEN1
SCHEMBL14426193 0.98 KDM4E (0.37) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL14426205 0.98 KDM4E (0.37) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL14426195 0.98 KDM4E (0.37) KDM4EATML3MBTL1GP6MEN1
SCHEMBL25661268 0.97 KDM4E (0.40) KDM4EATML3MBTL1GP6MEN1
SCHEMBL25661271 0.97 KDM4E (0.40) KDM4EATML3MBTL1GP6MEN1
SCHEMBL25661196 0.97 KDM4E (0.40) KDM4EATML3MBTL1GP6MEN1
SCHEMBL25661222 0.97 KDM4E (0.40) KDM4EATML3MBTL1GP6MEN1
SCHEMBL25661224 0.97 KDM4E (0.40) KDM4EATML3MBTL1GP6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed