Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 9/20 | 0.33 |
| ▸ | CNR2 | P34972 | 9/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MDH1 | P40925 | 1/20 | 0.31 |
| ▸ | MDH2 | P40926 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14428570 | 0.93 | CYP19A1 (0.46) | CYP17A1CYP19A1EPHX2MEN1POLB | |
| SCHEMBL2611802 | 0.86 | CYP17A1 (0.42) | CYP17A1CYP19A1EPHX2MEN1POLB | |
| SCHEMBL14428546 | 0.83 | CYP17A1 (0.40) | CYP17A1CYP19A1MAPTPTPN1PTPN11 | |
| SCHEMBL14428545 | 0.83 | CYP17A1 (0.49) | CYP17A1CYP19A1CNR2EPHX2MEN1 | |
| SCHEMBL2611804 | 0.82 | CYP17A1 (0.39) | CYP17A1CYP19A1CNR2EPHX2HIF1A | |
| SCHEMBL16406573 | 0.80 | CYP17A1 (0.45) | CYP17A1CYP19A1MEN1POLBMAPT | |
| SCHEMBL16426124 | 0.79 | CYP17A1 (0.44) | CYP17A1CYP19A1CNR2EPHX2MEN1 | |
| SCHEMBL14428538 | 0.79 | EPHX2 (0.34) | CNR1CNR2EPHX2MEN1MAPT | |
| SCHEMBL2611814 | 0.79 | CNR1 (0.35) | CNR1CNR2PTPN1PTPN11 | |
| SCHEMBL17032002 | 0.78 | CYP17A1 (0.51) | CYP17A1CYP19A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190451-A1 | Calixresorcinarene compounds, photoresist base materials, and compositions thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |