SCHEMBL1442864

SCHEMBL1442864

NC(=O)C[C@H](NC(=O)CNC(=O)[C@@H](N)CC(N)=O)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
GSTK1 Q9Y2Q3 1/20 0.46
GLO1 Q04760 1/20 0.41
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PDCD1LG2 Q9BQ51 1/20 0.34
CD274 Q9NZQ7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6129324 1.00 PTGS1 (0.46) PTGS1GSTK1GLO1OPRM1OPRD1
SCHEMBL2169172 1.00 PTGS1 (0.46) PTGS1GSTK1GLO1OPRM1OPRD1
SCHEMBL8014827 1.00 PTGS1 (0.46) PTGS1GSTK1GLO1OPRM1OPRD1
SCHEMBL9067746 0.97 PTGS1 (0.44) PTGS1GSTK1GLO1OPRM1OPRD1
SCHEMBL17479694 0.97 PTGS1 (0.48) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL153301 0.97 PTGS1 (0.48) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8135287 0.96 PTGS1 (0.45) PTGS1GSTK1GLO1OPRM1OPRD1
SCHEMBL8431345 0.96 PTGS1 (0.45) PTGS1GSTK1GLO1OPRM1OPRD1
SCHEMBL9225749 0.94 PTGS1 (0.44) PTGS1GSTK1GLO1OPRM1OPRD1
SCHEMBL17479582 0.94 PTGS1 (0.46) PTGS1GSTK1GLO1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116790569-B Pyruvic acid decarboxylase mutant and application thereof in preparation of alpha-hydroxyketone compound 杭州酶易生物技术有限公司 2024-04-26 CN disclosed
CN-112806471-B Feed additive composition 杜邦营养生物科学有限公司 2024-03-12 CN disclosed
CN-110139933-B Ataxin expression constructs 英特瑞克斯顿股份有限公司 2024-03-08 CN disclosed
CN-114854708-B Cordyceps militaris membrane protein beta-1, 3-glucan synthase and preparation method and application thereof 江苏大学 2024-01-30 CN disclosed
CN-114874303-B Antifungal peanut glycan thaumatin protein and preparation and application thereof 广州申晶雅农业科技有限公司 2023-11-24 CN disclosed
CN-116790569-A Pyruvic acid decarboxylase mutant and application thereof in preparation of alpha-hydroxyketone compound 杭州酶易生物技术有限公司 2023-09-22 CN disclosed
CN-111961137-B Fusion protein with bionic endothelial cell function and application thereof 南开大学 2023-09-05 CN disclosed
CN-110914416-B Microorganism and method for producing cannabinoids and cannabinoid derivatives 加州大学董事会 2023-07-21 CN disclosed
CN-112852865-B Oaan-1 protein, coding gene and application of related biological material thereof 中国科学院遗传与发育生物学研究所 2023-04-07 CN disclosed
CN-115397448-A Delivery of sialidases to cancer cells, immune cells and tumor microenvironment 安迅生物制药公司 2022-11-25 CN disclosed
WO-1997042314-A1 NUCLEIC ACID ENCODING SPINOCEREBELLAR ATAXIA-2 AND PRODUCTS RELATED THERETO CEDARS-SINAI MEDICAL CENTER (US) 1997-11-13 WO disclosed
CN-1159828-A Process for manufacture of a modified collagen-induced platelet aggregation inhibitor pallidipin SCHERING AG (DE) 1997-09-17 CN disclosed
EP-0781334-A1 PROCESS FOR MANUFACTURE OF A MODIFIED COLLAGEN-INDUCED PLATELET AGGREGATION INHIBITOR PALLIDIPIN SCHERING AKTIENGESELLSCHAFT (DE) 1997-07-02 EP disclosed
WO-1997022692-A1 NOVEL XYLANASES, GENES ENCODING THEM, AND USES THEREOF Röhm Enzyme Finland OY (FI) 1997-06-26 WO disclosed
WO-1996030402-A1 NUCLEOTIDE AND PROTEIN SEQUENCES OF LATS GENES AND METHODS BASED THEREON YALE UNIVERSITY (US) 1996-10-03 WO disclosed
WO-1996022307-A1 GENES ENCODING AN INSECT CALCIUM CHANNEL THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1996-07-25 WO disclosed
WO-1996022361-A1 GENE ENCODING AN INVERTEBRATE α1CALCIUM CHANNEL SUBUNIT THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1996-07-25 WO disclosed
WO-1996008563-A1 PROCESS FOR MANUFACTURE OF A MODIFIED COLLAGEN-INDUCED PLATELET AGGREGATION INHIBITOR PALLIDIPIN SCHERING AKTIENGESELLSCHAFT (DE) 1996-03-21 WO disclosed
EP-0598011-A1 ECDYSTEROID DEPENDENT REGULATION OF GENES IN MAMMALIAN CELLS GENENTECH, INC. (US) 1994-05-25 EP disclosed
WO-1993003162-A1 ECDYSTEROID DEPENDENT REGULATION OF GENES IN MAMMALIAN CELLS GENENTECH, INC. (US) 1993-02-18 WO disclosed