Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731861 | 0.98 | EPHX1 (0.52) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| SCHEMBL27966662 | 0.98 | EPHX1 (0.52) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| SCHEMBL27150348 | 0.98 | EPHX1 (0.52) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| SCHEMBL2420545 | 0.98 | EPHX1 (0.52) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| SCHEMBL21122034 | 0.98 | EPHX1 (0.52) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| SCHEMBL9539874 | 0.98 | EPHX1 (0.52) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| SCHEMBL28041964 | 0.98 | EPHX1 (0.52) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| SCHEMBL11743177 | 0.93 | — | — | |
| SCHEMBL30656129 | 0.85 | EPHX1 (0.48) | HDAC3HDAC1HDAC2EPHX1HDAC11 | |
| Formic Acid SCHEMBL17064245 | 0.85 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565611-A2 | METHOD OF REMOVING PRINTING INK FROM WASTE PAPER BY FLOTATION DEINKING | Degussa AG (DE) | 2005-08-24 | — | — | EP | claimed |
| WO-2004048680-A2 | METHOD OF REMOVING PRINTING INK FROM WASTE PAPER BY FLOTATION DEINKING | DEGUSSA AG (DE) | 2004-06-10 | — | — | WO | claimed |
| CN-110191878-A | Bicyclic [1.1.1] pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease | 德州大学系统董事会 | 2019-08-30 | — | — | CN | disclosed |
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | disclosed |
| EP-2521727-A1 | NOVEL BENZOIC PYRROLOPYRIDINE DERIVATIVES | Laboratoires Fournier S.A. (FR) | 2012-11-14 | — | — | EP | disclosed |
| EP-2475642-A1 | USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE APPLICATION THEREOF AS A MEDICAMENT FOR THE TREATMENT OF PARKINSON'S DISEASE | Laboratoires Fournier S.A. (FR) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011083278-A1 | NOVEL BENZOIC PYRROLOPYRIDINE DERIVATIVES | LABORATOIRES FOURNIER SA (FR) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011030068-A1 | USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE APPLICATION THEREOF AS A MEDICAMENT FOR THE TREATMENT OF PARKINSON'S DISEASE | LABORATOIRES FOURNIER SA (FR) | 2011-03-17 | — | — | WO | disclosed |
| US-4401675-A | Fungicidal carbazates | MONTEDISON S.P.A. (IT) | 1983-08-30 | — | — | US | disclosed |