SCHEMBL14430784

SCHEMBL14430784

CCCc1c2c(c(OC(F)F)c3ccccc13)CN(c1ccc(CC(=O)OCC)cc1Cl)C2=O

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14430786 0.94 PTGER4 (0.57) PTGER4
SCHEMBL14430703 0.92 PTGER4 (0.56) PTGER4
SCHEMBL14430787 0.91 PTGER4 (0.57) PTGER4
SCHEMBL14303712 0.91 PTGER4 (0.59) PTGER4
SCHEMBL12002028 0.90 PTGER4 (0.56) PTGER4
SCHEMBL10058575 0.90 PTGER4 (0.71) PTGER4
SCHEMBL10058581 0.89 PTGER4 (0.63) PTGER4
SCHEMBL10058587 0.89 PTGER4 (0.61) PTGER4
SCHEMBL10058586 0.89 PTGER4 (0.61) PTGER4
SCHEMBL14430839 0.88 PTGER4 (0.64) PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007088189-A1 BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN GLAXO GROUP LIMITED (GB) 2007-08-09 WO disclosed