Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 11/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431077 | 0.95 | PTGER4 (0.48) | PTGER4CYP1A2CYP2D6LTB4RLTB4R2 | |
| SCHEMBL10058498 | 0.93 | PTGER4 (0.54) | PTGER4CYP1A2CYP2D6LTB4RLTB4R2 | |
| SCHEMBL10058524 | 0.92 | PTGER4 (0.57) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL14431078 | 0.90 | PTGER4 (0.47) | PTGER4CYP1A2CYP2D6PPARGPPARD | |
| SCHEMBL10058523 | 0.89 | PTGER4 (0.50) | PTGER4CYP1A2CYP2D6LTB4RLTB4R2 | |
| SCHEMBL10058520 | 0.88 | PTGER4 (0.49) | PTGER4CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL9606782 | 0.87 | PTGER4 (0.54) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL13942570 | 0.87 | PTGER4 (0.59) | PTGER4CYP1A2CYP2D6LTB4RLTB4R2 | |
| SCHEMBL9606761 | 0.85 | PTGER4 (0.61) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL14430780 | 0.84 | PTGER4 (0.47) | PTGER4CYP1A2CYP2D6LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088189-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | WO | disclosed |