Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 19/20 | 0.54 |
| ▸ | CHUK | O15111 | 17/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228836 | 0.84 | IKBKB (0.76) | IKBKBCHUK | |
| SCHEMBL14431733 | 0.81 | IKBKB (0.74) | IKBKBCHUK | |
| SCHEMBL14431694 | 0.78 | IKBKB (0.69) | IKBKBCHUK | |
| SCHEMBL14431755 | 0.78 | IKBKB (0.69) | IKBKBCHUK | |
| SCHEMBL14431805 | 0.75 | IKBKB (0.72) | IKBKBCHUK | |
| SCHEMBL14432239 | 0.74 | IKBKB (0.72) | IKBKBCHUK | |
| SCHEMBL14431661 | 0.72 | IKBKB (0.56) | IKBKBCHUK | |
| SCHEMBL14431823 | 0.71 | IKBKB (0.62) | IKBKBCHUK | |
| SCHEMBL14431542 | 0.70 | IKBKB (1.00) | IKBKBCHUK | |
| SCHEMBL5228780 | 0.70 | IKBKB (0.56) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490371-B1 | THIOPHENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL MYERS SQUIBB CO (US) | 2007-08-15 | — | — | EP | disclosed |