Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 19/20 | 0.65 |
| ▸ | CHUK | O15111 | 18/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431786 | 0.97 | IKBKB (0.63) | IKBKBCHUK | |
| SCHEMBL14432460 | 0.96 | IKBKB (0.62) | IKBKBCHUK | |
| SCHEMBL14431788 | 0.93 | IKBKB (0.67) | IKBKBCHUK | |
| SCHEMBL5234563 | 0.86 | IKBKB (0.58) | IKBKBCHUK | |
| SCHEMBL14431542 | 0.79 | IKBKB (1.00) | IKBKBCHUK | |
| SCHEMBL14432457 | 0.79 | IKBKB (0.63) | IKBKBCHUK | |
| SCHEMBL5228997 | 0.77 | IKBKB (0.61) | IKBKBCHUK | |
| SCHEMBL5228836 | 0.77 | IKBKB (0.76) | IKBKBCHUK | |
| SCHEMBL14431641 | 0.75 | IKBKB (0.62) | IKBKBCHUK | |
| SCHEMBL14431729 | 0.75 | IKBKB (0.72) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490371-B1 | THIOPHENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL MYERS SQUIBB CO (US) | 2007-08-15 | — | — | EP | disclosed |