SCHEMBL14433147

SCHEMBL14433147

O=C(/C=C/c1ccc([N+](=O)[O-])cc1)OCl

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.57
MAOA P21397 5/20 0.57
BCHE P06276 1/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
PTGS1 P23219 1/20 0.54
PTGS2 P35354 1/20 0.54
APP P05067 1/20 0.53
CYP1B1 Q16678 1/20 0.53
FBP1 P09467 1/20 0.51
POLB P06746 2/20 0.51
HSPD1 P10809 1/20 0.51
HSPE1 P61604 1/20 0.51
MAPT P10636 1/20 0.51
KRAS P01116 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15367534 0.83 MAOB (0.61) MAOBMAOABCHEMEN1KMT2A
SCHEMBL5315888 0.83 MAOB (0.61) MAOBMAOABCHEMEN1KMT2A
SCHEMBL522693 0.83 CA12 (0.62) MAOBMAOABCHEMEN1KMT2A
SCHEMBL17355377 0.83 MAOB (0.61) MAOBMAOABCHEMEN1KMT2A
SCHEMBL9523424 0.83 MAOB (0.61) MAOBMAOABCHEMEN1KMT2A
SCHEMBL1231449 0.83 CA12 (0.62) MAOBMAOABCHEMEN1KMT2A
SCHEMBL42325 0.82 MEN1 (0.71) MAOBMAOABCHEMEN1KMT2A
SCHEMBL277169 0.82 MEN1 (0.71) MAOBMAOABCHEMEN1KMT2A
SCHEMBL737053 0.81 MAOB (0.62) MAOBMAOABCHEMEN1KMT2A
SCHEMBL737052 0.81 MAOB (0.62) MAOBMAOABCHEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1815872-A1 COMPOSITION FOR AMYLOID-ASSOCIATED DISEASE DIAGNOSIS Nagasaki University (JP) 2007-08-08 EP disclosed