Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | LYN | P07948 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218116 | 0.90 | MEN1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL30589615 | 0.85 | MEN1 (0.74) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL6436269 | 0.85 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL28564087 | 0.85 | MEN1 (0.74) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL12218594 | 0.84 | KMT2A (0.72) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL6227015 | 0.83 | MEN1 (0.71) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL16500681 | 0.82 | KMT2A (0.79) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL31054239 | 0.82 | MEN1 (0.64) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL16946692 | 0.82 | GRIK1 (0.70) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL14751411 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087424-A2 | METHOD OF TREATING KCNQ RELATED DISORDERS USING ORGANOZINC COMPOUNDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-08-02 | — | — | WO | disclosed |