Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | CFD | P00746 | 3/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371449 | 0.91 | F10 (0.57) | F10KLKB1USP30CFDKMT2A | |
| SCHEMBL14434230 | 0.85 | F10 (0.47) | F10KLKB1CFDKMT2ANPSR1 | |
| SCHEMBL12101325 | 0.84 | F10 (0.51) | F10KLKB1CFDSLC2A1 | |
| SCHEMBL14434235 | 0.84 | F10 (0.45) | F10KLKB1CFDSLC2A1NPSR1 | |
| SCHEMBL14434228 | 0.82 | F10 (0.44) | F10KLKB1CFDSLC2A1KMT2A | |
| SCHEMBL14434220 | 0.82 | NPC1 (0.47) | F10CFDKMT2AALDH1A1NPC1 | |
| SCHEMBL12371463 | 0.82 | MELK (0.51) | F10KLKB1CFDSLC2A1KMT2A | |
| SCHEMBL14434240 | 0.82 | MELK (0.51) | F10KLKB1CFDSLC2A1KMT2A | |
| SCHEMBL14434994 | 0.80 | NPC1 (0.46) | F10KLKB1CFDKMT2AALDH1A1 | |
| SCHEMBL12101301 | 0.80 | F10 (0.53) | F10KLKB1CFDSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093595-A1 | SUBSTITUTED PROLINAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |