Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 16/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667203 | 0.86 | RAF1 (0.61) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL101455 | 0.83 | RAF1 (0.42) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4781956 | 0.83 | RAF1 (0.42) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4164656 | 0.81 | RAF1 (0.41) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4169623 | 0.81 | RAF1 (0.44) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4769749 | 0.79 | RAF1 (0.43) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL101454 | 0.78 | RAF1 (0.39) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL19687669 | 0.78 | RAF1 (0.42) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL19838123 | 0.77 | RAF1 (0.42) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4979550 | 0.76 | NPSR1 (0.65) | RAF1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093365-A2 | NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2007-08-23 | — | — | WO | disclosed |