Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21468398 | 0.79 | — | — | |
| SCHEMBL13948748 | 0.78 | HRH3 (0.30) | — | |
| SCHEMBL13768544 | 0.75 | PTGS1 (0.36) | LMNAKMT2A | |
| SCHEMBL16257980 | 0.74 | TP53 (0.31) | — | |
| SCHEMBL13895726 | 0.73 | USP5 (0.33) | USP5LMNASMN1; SMN2 | |
| SCHEMBL12742127 | 0.73 | RNPEP (0.30) | — | |
| SCHEMBL12332682 | 0.71 | — | — | |
| SCHEMBL24258419 | 0.71 | GABRR1 (0.30) | — | |
| SCHEMBL24295272 | 0.71 | KDM4E (0.30) | — | |
| SCHEMBL14788904 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089745-A2 | NOVEL COMPOUNDS WITH HIGH THERAPEUTIC INDEX | SIGNATURE R & D HOLDINGS, LLC (US) | 2007-08-09 | — | — | WO | disclosed |