Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.79 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | HTR2B | P41595 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.67 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.67 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.63 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21594386 | 1.00 | HSD17B10 (0.79) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| SCHEMBL30189533 | 0.89 | HSD17B10 (0.79) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| SCHEMBL11159811 | 0.89 | HSD17B10 (0.79) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| SCHEMBL11159809 | 0.89 | HSD17B10 (0.79) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| Cephalexin Anhydrous SCHEMBL11985597 | 0.88 | HSD17B10 (1.00) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| Cephalexin Anhydrous SCHEMBL10925361 | 0.88 | HSD17B10 (1.00) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| Cephalexin Anhydrous SCHEMBL8467348 | 0.88 | HSD17B10 (1.00) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| Cephalexin Anhydrous SCHEMBL20703090 | 0.88 | HSD17B10 (1.00) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| Cephalexin Anhydrous SCHEMBL8481524 | 0.88 | HSD17B10 (1.00) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 | |
| Cephalexin Anhydrous SCHEMBL6663545 | 0.88 | HSD17B10 (1.00) | HSD17B10ALDH1A1KMT2AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259141-B2 | Vancomycin analogs and methods thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-21 | — | — | US | disclosed |
| US-7259141-B2 | Vancomycin analogs and methods thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-21 | — | — | US | disclosed |