Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23766314 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL31181818 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL24384254 | 0.80 | TSHR (0.30) | TSHR | |
| SCHEMBL1468864 | 0.74 | LPAR3 (0.38) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL10764275 | 0.73 | SLC6A2 (0.31) | — | |
| SCHEMBL3418214 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL12664747 | 0.71 | MAPT (0.48) | TSHRALDH1A1USP2LMNAABCC4 | |
| SCHEMBL13258720 | 0.71 | SLC6A2 (0.33) | — | |
| SCHEMBL18187333 | 0.71 | TSHR (0.69) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL10772647 | 0.71 | TSHR (0.69) | TSHRALDH1A1TDP1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088187-A1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2007-08-09 | — | — | WO | disclosed |