Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461625 | 0.92 | CYP19A1 (0.40) | CYP19A1CYP2A6CFTRSLC6A2SLC6A4 | |
| SCHEMBL4458972 | 0.88 | CFTR (0.41) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4462104 | 0.88 | CFTR (0.42) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4470641 | 0.84 | POLB (0.37) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4458274 | 0.81 | CYP19A1 (0.49) | CYP19A1KCNA5CYP3A4CYP3A5L3MBTL1 | |
| SCHEMBL4459552 | 0.80 | KCNA5 (0.42) | CYP19A1KCNA5CYP3A4GRM5KCNH2 | |
| SCHEMBL4459564 | 0.79 | CYP19A1 (0.36) | CYP19A1KCNA5 | |
| SCHEMBL4470602 | 0.79 | KCNA5 (0.35) | CYP19A1KCNA5 | |
| SCHEMBL4463302 | 0.78 | TAAR1 (0.35) | KCNA5CYP3A4CYP3A5 | |
| SCHEMBL4453054 | 0.78 | TAAR1 (0.38) | KCNA5KCND3CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089679-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2007-08-09 | — | — | WO | disclosed |